Analysis Hyperlinks Adversarial Childhood Experiences to Accelerated Getting old
Unwanted childhood experiences have more than just mental and emotional effects. Growing up with abuse and violence at a time when we have very little power over our lives is also detrimental to our physical health. While the effects may take many years or we may dismiss things as “growing up too fast”, it is still devastating.
Fortunately, if we understand how trauma Affecting us at the cellular level, we can take our health into our own hands. With possible implications for COVID-19, this is more important than ever.
How adverse childhood experiences lead to accelerated aging
For this study, the researchers analyzed nearly 80 articles with a total of 116,000 participants. They found that Children exposed to abuse, violence or other threatening trauma showed faster aging at the cellular level. This included shortened Telomeres, the protective caps on our chromosomes that shorten with each department. If they get too short, the cell can no longer divide and becomes senescent. It complements the evidence from 2014 that suggests that at least in African American boys Growing up in a socially disadvantaged environment can shorten telomeres by up to 40 percent.
The impact of childhood trauma on aging was identified may also be associated with prior pubertyit may have evolutionary “advantages”. A violent, threatening world creates more pressure to reproduce earlier so that genes can be passed on before death.
While this adjustment may have benefited our species’ survival in the past, it does not alleviate the suffering of those affected by negative childhood experiences. Nor is it any comfort to those of us who are close to someone who had them. The question is, what can we do to restore the length of our telomeres and rejuvenate our bodies?
A closer look at the safety of telomeres elongation
Some researchers believe that longer telomeres are a risk factor for cancer. This is because tumor cells renew their telomeres each time they divide so that the cancer can continue to grow. However, a laboratory study found this to be the case Telomerase gene therapy was able to significantly extend the lifespan of mice without causing an increase in cancer. One year old (middle aged) mice had a 24 percent longer lifespan. Two-year-old mice (elderly) lived 13 percent longer. The safety of this therapy may depend on the type of viral vector used. Adeno-associated viruses (AAVs) do not have significant effects on rapidly growing cells and preferentially target cells that do not divide strongly.
What about people A study of 143 people over the age of 60 found this shorter telomeres were associated with higher mortality rates. This was caused in part by a 3.18 times higher risk of death Heart diseaseand an 8.54 times higher risk of death of infectious disease. Because many immune cells have to divide in response to infection, short telomeres can increase the risk of complications. This includes severe COVID-19 infections. Older adultsMen and people with cardiometabolic disorders are the most vulnerable groups and all have shorter telomeres.
Can we restore telomere length?
The enzyme telomerase, which the human body can produce, rebuilds telomeres after each cell division. Gene therapies are considered to be the most effective intervention for increasing telomerase, but human clinical trials have not yet started. Fortunately, there are natural ways to increase telomere length that are not only cheaper, but probably also safer.
For example, a study of a supplementary nutrient mix found that participants were randomized to take them had longer telomeres at the end of the study than the control group. There was a difference of approximately 1,000 base pairs (1 kb) between the supplement and control groups. To put this in perspective, the average person is born just over nine kb.
The supplement regimen included vitamin D, the B vitamins, vitamins K2 and E; Omega-3 fatty acids and gamma linoleic acid (GLA); Ubiquinol (the active form of coenzyme Q10 and a broad spectrum probiotic. Vitamin B12 and folic acid are necessary for DNA function and repair, while deficiencies can accelerate telomeres shortening. Vitamin D, vitamin E, carotenoids and CoQ10 protect the telomeres due to their antioxidant and anti-inflammatory effects. At HoneyColony, We carry the Telomeron formula, which contains omega-3 fats, B vitamins, carotenoids and vitamin D..
Omega-3 fatty acids can also protect telomeres by reducing inflammation and oxidative stress. Another clinical study tested omega-3 fatty acid supplementation An increased ratio of omega-3 to omega-6 fatty acids was associated with elongated telomeres. On average, they decreased by 43 base pairs in the placebo group, but increased by 21 and 50 base pairs in the low (1.25 g) and high (2.5 g) groups, respectively.
Astragalus and age-related diseases
The herbal remedy Astragalus membranaceusAs a proprietary extract TA-65 could also help restore telomere length. A study of people with age-related macular degeneration (AMD) found this Taking TA-65 for one year significantly improved macular function.
Your values for impaired eye sensitivity improved from -39.6 percent to -31.7 percent. There was no change in the placebo group. Measurements of eye sensitivity are more objective than visual acuity, which can persist until advanced AMD. Short telomeres play a role in AMD, so the results of this study likely came from an increase in telomerase.
Lifestyle interventions to increase telomerase
One lifestyle intervention that can help rebuild telomeres is meditation. When women who recently recovered from breast cancer practiced Mindful Stress Reduction Techniques (MBSR), their telomerase levels increased compared to the control group. Her average telomere length did not increase, but the duration of the study was not long enough to see this effect.
MBSR includes both sitting and walking meditation. It also includes body scanning (where physical sensations are observed) and gentle hatha yoga poses. The “therapeutic dose” of meditation was 15 minutes per day of formal practice plus an additional 15-45 minutes of “informal” practice during daily activities.
Exercise, including cardio training can also protect our telomeres. When older endurance athletes were compared to their non-athletes of the same age, their ratio of telomeres to “normal” DNA, which codes for genetic information, was higher. While non-athletes had a ratio of 0.92, the average ratio of trained athletes was 1.12. The average ratio of young athletes was 1.47, so endurance training alone is only partially protective. Telomere length was also linked to their cardiovascular fitness.
If you or someone close to you had negative childhood experiences, you don’t have to put up with a fate of accelerated aging. By protecting telomeres and increasing telomerase to rebuild them, a brighter future is possible.
Alexandra Preston is an Australian Naturopath who is passionate about empowering others to take responsibility for their health and healing the planet. Her particular interest in natural health is anti-aging. She also loves the beach and is a semi-professional dancer.
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