COVID-19 now probably main reason for dying amongst 25-44’s in USA

Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), has afflicted people from all walks of life worldwide. High-risk populations are at increased risk of serious illness and death, including the elderly and those with underlying diseases.

The COVID-19 has resulted in a significant increase in all cause deaths in the United States, particularly among the elderly over 65 years of age. Because younger adults have lower infectious mortality rates, little attention has been paid to the mortality burden from COVID-19 in this age group.

A team of researchers from Brigham and Women’s Hospital, Harvard Medical School’s Emergency Medicine Department, aimed to determine changes in all-cause mortality or excessive deaths in adults between the ages of 25 and 44 in the United States. In addition, they would also like to identify the Years of Lost Life (YLL) in this age group.

The study

The team used data from the National Center for Health Statistics from the US Centers for Disease Control and Prevention (CDC) to arrive at the study results. The data consists of the latest public data on all-cause mortality between 2019-2020, unintentional deaths from drug overdose, unintentional opioid-specific deaths, and COVID-19 deaths in adults aged 25 to 44 during the COVID-19 pandemic in the country .

The team compared COVID-19-related deaths in the pandemic age group to all drug overdose deaths and opioid-specific overdose deaths in each of the 10 Health and Social Services (HHS) regions in 2018, the most recent year for the Data is available.

They also calculated for the YLL due to COVID-19 and for all deaths that occurred between March and July. Excess mortality means the deaths in 2020 minus the deaths in 2019 in the corresponding period.

Unintentional overdose deaths, opioid deaths, and COVID-19 deaths among persons aged 25-44, per 100,000 person-month (vertical axis) by month (horizontal axis), stratified by HHS region. Bars: Unintentional drug overdose deaths (ICD10 X41-X45, Y11-Y15), 2018 (light blue with 95% CI) and opioid-specific drug overdose deaths (ICD10 X41-X45, Y11-Y15 and T40.0-40.6), 2018 (dark blue with 95% CI). Lines: COVID-19 deaths (ICD10 U071), 2020; colors are stratified by regional COVID-19 case incidence per 1,000,000 residents through July 31, 2020 (green <1,050 cases per 100,000 residents; yellow 1,050-1,499 cases per 100,000 residents; red >1,500 cases per 100,000 population).  HHS Regions: Region 1: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont;  Region 2: New Jersey and New York;  Region 3: Delaware, District of Columbia, Maryland, Pennsylvania, Virginia, and West Virginia;  Region 4: Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee;  Region 5: Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin;  Region 6: Arkansas, Louisiana, New Mexico, Oklahoma, and Texas;  Region 7: Iowa, Kansas, Missouri, and Nebraska;  Region 8: Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming;  Region 9: Arizona, California, Hawaii, and Nevada;  Region 10: Alaska, Idaho, Oregon, and Washington.  “Height =” 670 “src =” https://www.news-medical.net/image.axd?picture=2020%2f10%2f%40_2020.10.21.20217174v1 .jpg “srcset =” https: // www. news-medical.net/image.axd?picture=2020%2f10%2f%40_2020.10.21.20217174v1.jpg&ts=20201026012835&ri=1200 1200w, https://www.news -medical.net/image.axd?picture=2020 % 2f10% 2f% 40_2020.10.21.20217174v1.jpg & ts = 20201026012835 & ri = 1150 1150w, https://www.news-medical.net/image.axd?picture=2020% 2f10% 2f% 40_2020.10.21.20217174v1.jpg & ts = 20201026012835 & ri = 950 950w, https://www.news-medical.net/image.axd?picture=2020%2f10%2f%40_2020.10.21.202174121 = 750 750w, https: //www.news- medical.net/image.axd?picture=2020%2f10%2f%40_2020.10.21.20217174v1.jpg&ts=20201026012835&ri=550 550w, https: //www.news-medical .net / image.axd?  picture = 2020% 2f10% 2f% 40_2020.10.21.20217174v1.jpg & ts = 20201026012835 & ri = 450 450w “Sizes =” (min-width: 1200px) 673px, (min-width: 1090px) 667px, (min-width : 992px) calc (66.6 vw – 60px), (min-wid th: 480px) calc (100vw – 40px), calc (100vw – 30px) “title =” Accidental Overdose Deaths, Opioid Deaths, and COVID-19 -Deaths in people aged 25 to 44 per 100,000 person-month (vertical axis) by month (horizontal axis) stratified by HHS region.  Bars: Accidental deaths from overdose (ICD10 X41-X45, Y11-Y15), 2018 (light blue with 95% CI) and opioid-specific deaths from overdose (ICD10 X41-X45, Y11-Y15 and T40.0-40.6), 2018 (dark blue with 95% CI).  Lines: COVID-19 Deaths (ICD10 U071), 2020;  The colors are stratified according to the regional COVID-19 incidence per 1,000,000 population by July 31, 2020 (green) <1,050 cases per 100,000 residents; yellow 1,050-1,499 cases per 100,000 residents; red >1,500 cases per 100,000 population).  HHS Regions: Region 1: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont;  Region 2: New Jersey and New York;  Region 3: Delaware, District of Columbia, Maryland, Pennsylvania, Virginia, and West Virginia;  Region 4: Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee;  Region 5: Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin;  Region 6: Arkansas, Louisiana, New Mexico, Oklahoma, and Texas;  Region 7: Iowa, Kansas, Missouri, and Nebraska;  Region 8: Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming;  Region 9: Arizona, California, Hawaii, and Nevada;  Region 10: Alaska, Idaho, Oregon, and Washington.  “Width =” 1200 “/><span itemprop=

Accidental overdose deaths, opioid deaths, and COVID-19 deaths in people aged 25 to 44 years per 100,000 person-month (vertical axis) per month (horizontal axis) stratified by HHS region. Bars: Accidental deaths from overdose (ICD10 X41-X45, Y11-Y15), 2018 (light blue with 95% CI) and opioid-specific deaths from overdose (ICD10 X41-X45, Y11-Y15 and T40.0-40.6), 2018 (dark blue with 95% CI). Lines: COVID-19 Deaths (ICD10 U071), 2020; The colors are stratified according to the regional COVID-19 incidence per 1,000,000 population by July 31, 2020 (green) <1,050 cases per 100,000 residents; yellow 1,050-1,499 cases per 100,000 residents; red >1,500 cases per 100,000 population). HHS Regions: Region 1: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont; Region 2: New Jersey and New York; Region 3: Delaware, District of Columbia, Maryland, Pennsylvania, Virginia, and West Virginia; Region 4: Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee; Region 5: Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin; Region 6: Arkansas, Louisiana, New Mexico, Oklahoma, and Texas; Region 7: Iowa, Kansas, Missouri, and Nebraska; Region 8: Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming; Region 9: Arizona, California, Hawaii, and Nevada; Region 10: Alaska, Idaho, Oregon, and Washington.

What the study found

In the study, which was published in the pre-print journal medRxiv *, the team found that more than 74,000 deaths occurred in adults between the ages of 25 and 44 between March and July 2020.

The number is 14 percent higher than the same period in 2019. In regions like New York, New Jersey, Louisiana, Arkansas, Oklahoma, New Mexico, Texas, California, Arizona, Nevada, and Hawaii, those associated with COVID-19 exceeded Deaths The accidental deaths from opioid overdose in 2018 for at least one month.

A total of 2,450 COVID-19 deaths were recorded in these states during the pandemic, compared to 2,445 opioid deaths in the same period in 2018. From March to July 2018, the US recorded 10,347 deaths related to opioid overdose, increasing to 472,608 YLL resulted in adults between 25 and 44 years of age.

Amid the pandemic, 4,055 COVID-19 deaths were recorded in the same age group, resulting in 175,631 YLL. When the team took into account all 14,155 deaths in 2020, young adults accounted for 627,872 YLL, surpassing the YLL due to deaths from overdose in the same period in 2018.

Based on the results of the study, the team concluded that COVID-19 is likely the leading cause of death among young adults in some areas of the United States during the pandemic. The team also found that in these regions, COVID-19-related mortality is similar to the human immunodeficiency virus (HIV) / acquired immunodeficiency syndrome (AIDS) epidemic at its peak in the country between 1994 and 1995.

US COVID-19 numbers

For months, the US has been the hardest hit country during the coronavirus pandemic. The country has now reported over 8.6 million cases and at least 225,000 deaths. New York reports the highest number of deaths at over 33,000.

In addition to the US, countries with high coronavirus cases include India with more than 7.86 million cases, Brazil with more than 5.38 million cases, Russia with more than 1.5 million cases, and France with more than 1.13 million Cases.

Globally, the number of COVID-19 cases has exceeded 42.92 million, and the infection has now claimed more than 1.15 million deaths. At least 28.89 million of these have already recovered.

* Important NOTE

medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be considered conclusive, guide clinical practice / health-related behavior, or treated as established information.

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